COAGADEX Is a High-Purity Factor X Product
COAGADEX is the first and only high-purity factor X product available in the U.S.
Composition of COAGADEX: % of total protein1
*Plasma-derived factor X concentrate. COAGADEX is the only FDA-licensed, plasma-derived factor X concentrate.
COAGADEX is the first and only product that is manufactured based on a factor X assay2
- Elevated levels of factors II, VII, and IX may be associated with an increased risk of thromboembolic complications4
- Other risk factors that can contribute to thrombotic risk include5:
For every 100 IU of factor X in COAGADEX, there is <1 IU of factors II, VII, or IX2
- Older age
- Traumatic injury
- Surgical intervention
- Birth control pills
- Being overweight or obese
References: 1. Data on file, BPL-RD050-0515. 2. COAGADEX® (Coagulation Factor X, Human) Prescribing Information. Durham, NC: BPL Limited. 2018. 3. Sorensen B, Spahn DR, Innerhofer P, et al. Crit Care. 2011;15:201. 4. Menegatti M, Peyvandi F. Semin Thromb Hemost. 2009;35:407-415. 5. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/deep-vein-thrombosis/symptoms- causes/syc-20352557. Accessed May 4, 2018. 6. Medical and Scientific Advisory Council (MASAC) of the National Hemophilia Foundation. MASAC Document #253. https://www.hemophilia.org/Researchers-Healthcare-Providers/Medical-and-Scientific-Advisory-Council-MASAC/MASAC-Recommendations/MASAC-Recommendations-Concerning-Products-Licensed-for-the-Treatment-of-Hemophilia-and-Other-Bleeding-Disorders. Accessed November 20, 2018.